Title:
トリフルオロメチルスルホニル化合物誘導体の製造方法
Document Type and Number:
Japanese Patent JP6664887
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide a method for producing a trifluoromethylsulfonyl compound derivative useful as synthetic intermediates for medicines and agrochemicals.SOLUTION: The method for producing a trifluoromethylsulfonyl compound derivative represented by formula (2) comprises reacting a sulfonyl fluoride derivative represented by formula (1) with trifluoromethane in an organic solvent in the presence of an organic strong base catalyst and a proton scavenger. In the method, the organic strong base is 1-tert-butyl-4,4,4-[tris(dimethylamino)-2,2-bis(tris(dimethylamino)phosphoranylidenamino]-2λ,4λ-catenadi. Formula (1): R-SO-F and formula (2): R-SO-CF(where R is a phenyl group, a phenyl group substituted with an alkyl group or halogen, a 4-biphenyl group or a 1- or 2-naphthyl group).SELECTED DRAWING: None
Inventors:
Tetsuo Shibata
Satoshi Okusu
Takumi Kagawa
Satoshi Okusu
Takumi Kagawa
Application Number:
JP2015084838A
Publication Date:
March 13, 2020
Filing Date:
April 17, 2015
Export Citation:
Assignee:
National Institute of Technology Nagoya Institute of Technology
Tosoh Finechem Co., Ltd.
Tosoh Finechem Co., Ltd.
International Classes:
C07C315/04; C07C317/14
Domestic Patent References:
| JP2014091691A |
Other References:
KOLOMEITSEV, A. A. et al.,A convenient route to aryl trifluoromethyl sulfones by fluoride-catalyzed cross-coupling of arenesulfonyl fluorides with (trifluoromethyl)trimethylsilane and (trifluoromethyl)trimethylstannane,SYNTHESIS,1990年,Vol.12,p.1151-1152
Attorney, Agent or Firm:
Koji Nagato