To provide a method for producing a water-soluble composition containing a coenzyme Q10, not causing deposition, precipitation or surfacing and retaining a homogeneous and stable water-soluble state even when the coenzyme Q10 formulated in a high concentration without using a dissolving medium such as oil and fat is stored for a long period and further, excellent in acid resistance, salt resistance and heat resistance and remarkably improved in in vivo absorbability.
The method for producing the water-soluble composition containing the coenzyme Q10 comprises carrying out homogenization of (A) 5-40 mass% coenzyme Q10, (B) 5-30 mass% monoester of polyglycerol having 10 average degree of polymerization with stearic acid, oleic acid or linoleic acid and (C) 1-18 mass% mono-, di- or triester of a polyglycerol having 3-6 average degree of polymerization with oleic acid or linoleic acid and (D) water.
ABE ATSUKO
MINEMURA TAKESHI
KUBOTA HIROTAKA
NISSHIN PHARMA INC
JP2000212066A | 2000-08-02 | |||
JPH07204487A | 1995-08-08 |
WO2001012229A1 | 2001-02-22 |
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