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Title:
METHOD FOR PRODUCTION DL-TOCOPHEROL COMPOUNDS AND INTERMEDIATE FOR PRODUCING THE SAME
Document Type and Number:
Japanese Patent JPH07300470
Kind Code:
A
Abstract:

PURPOSE: To easily obtain a dl-tocopherol compound in a good yield in a short process from an inexpensively available raw material by subjecting the specific compound to a reducing reaction.

CONSTITUTION: A compound of formula I [one of the bonds in the group of formula II is a single bond, and the other is a double bond; R1R3 are H, (substituted)hydrocarbon group; X is (protected)hydroxyl group; Y is-CH2-CH2-,- CH=CH-] is subjected e.g. to a catalytic hydrogen addition reaction in the presence of a contact catalyst such as Pd/C in a solvent such as an alcohol compound preferably at approximately 10-60C under a hydrogen pressure of approximately 1-3atm for about 1-2hr to obtain a dl-tocopherol compound of formula III. The compound includes 6-acetoxy-2,5,7,8-tetramethyl-2-(4',8', 12'- trimethyltridecyl) chromane of formula IV.


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Inventors:
KANEKO TATSUHIKO
KASHIWA KENICHI
Application Number:
JP4738095A
Publication Date:
November 14, 1995
Filing Date:
March 07, 1995
Export Citation:
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Assignee:
TAKEDA CHEMICAL INDUSTRIES LTD
International Classes:
C07D311/72; A61K31/352; A61K31/355; A61P3/02; C07C33/048; C07C43/23; C07C50/06; (IPC1-7): C07D311/72; C07C33/048; C07C50/06; C07D311/72
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)