Title:
METHOD FOR PRODUCTION OF IPS CELLS USING NON-VIRAL APPROACH
Document Type and Number:
Japanese Patent JP2018007667
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a method for the production of IPS cells using non-viral approach.SOLUTION: According to the present invention, there are provided a method and composition for induction of pluripotent stem cells and other desired cell types. For example, there is provided a method for generating essentially vector-free induced pluripotent stem cells. Furthermore, there are further provided induced pluripotent stem cells and desired cell types essentially free of exogenous vector elements with the episomal expression vectors to express differentiation programming factors.SELECTED DRAWING: None
Inventors:
AMANDA MACK
JAMES THOMSON
JAMES THOMSON
Application Number:
JP2017132684A
Publication Date:
January 18, 2018
Filing Date:
July 06, 2017
Export Citation:
Assignee:
CELLULAR DYNAMICS INT INC
International Classes:
C12N15/09; C12N5/074; C12N5/10
Foreign References:
| WO2007069666A1 | 2007-06-21 |
Other References:
GENE THERAPY, 2001, VOL.8, PP.1508-1513, JPN6018015890, ISSN: 0004171179
SIENCE, 2007, VOL.318, PP.1917-1920, JPN6018015891, ISSN: 0004171180
NATURE, 2008.01, VOL.451, NO.7175, PP.141-147, JPN6016033353, ISSN: 0004171181
STEM CELLS, 2006, VOL.24, NO.5, PP.1338-1347, JPN6016033354, ISSN: 0004171182
再生医療, 2008.05, VOL.7, NO.2, PP.171-177, JPN6016034605, ISSN: 0004171183
PROC. NATL. ACAD. SCI. USA, 2003, VOL.100, NO.24, PP.14269-14274, JPN6016033355, ISSN: 0004171184
SIENCE, 2007, VOL.318, PP.1917-1920, JPN6018015891, ISSN: 0004171180
NATURE, 2008.01, VOL.451, NO.7175, PP.141-147, JPN6016033353, ISSN: 0004171181
STEM CELLS, 2006, VOL.24, NO.5, PP.1338-1347, JPN6016033354, ISSN: 0004171182
再生医療, 2008.05, VOL.7, NO.2, PP.171-177, JPN6016034605, ISSN: 0004171183
PROC. NATL. ACAD. SCI. USA, 2003, VOL.100, NO.24, PP.14269-14274, JPN6016033355, ISSN: 0004171184
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
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