To provide an improved profitable method for racemizing an optically active amine, by which the objective product having a high racemization degree can simultaneously be obtained in a high racemization yield (racemate yield).
This method for racemizing the optically active amine, comprising reacting an optically active amine represented by formula I (R1 and R2 are different from each other; R1, R2, and R3 are each an alkyl, a cycloalkyl, an arylalkyl, an aryl, a heteroaryl or a heterocyclic group; R3 may additionally be H; provided that the above-described groups each may have one or more substituents selected from alkyl groups, cycloalkyl groups, alkoxy groups, aryloxy groups, amino groups, alkylamino groups and dialkylamino groups) in the presence of hydrogen and a hydrogenation catalyst or dehydrogenation catalyst at an enhanced temperature, is characterized in that the catalyst contains copper and zinc oxide as active catalyst components and a carrying material.
LIANG SHELUE
KRAMER ANDREAS DR
STUERMER RAINER DR
HOEHN ARTHUR
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