Title:
放射線の照射を用いたペルオキシレドキシンのシャペロン活性調節方法
Document Type and Number:
Japanese Patent JP5684397
Kind Code:
B2
Abstract:
The present invention relates to a method for increasing chaperone activity by irradiating peroxiredoxin (Prx) proteins. More particularly, the present invention may be useful for preparing recombinant proteins imparting resistance against various environmental stresses by increasing the chaperone activity of peroxiredoxin, since it has been observed that irradiated peroxiredoxin has enhanced chaperone activity characteristics, wherein an α-helix structure decreases while a β-sheet structure increases, from analysis results of a protein structure change and chaperone activity after irradiating two types of peroxiredoxins (2-Cys, 3-Cys) which are two active cysteine motifs of peroxiredoxin.
Inventors:
チュン、ビュン ヨプ
イ、スン シク
アン、ビュン チュル
イ、ウン ミ
イ、ジェ テク
ぺ、ヒュン−ウ
イ、スン シク
アン、ビュン チュル
イ、ウン ミ
イ、ジェ テク
ぺ、ヒュン−ウ
Application Number:
JP2013534829A
Publication Date:
March 11, 2015
Filing Date:
October 25, 2011
Export Citation:
Assignee:
コリア アトミック エナジー リサーチ インスティテュート
International Classes:
C12N9/08
Attorney, Agent or Firm:
Makoto Onda
Hironori Onda
Jun Honda
Hironori Onda
Jun Honda