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Title:
METHOD FOR SEPARATING OPTICALLY ACTIVE SUBSTANCE BY FORMATION OF HELICAL MOLECULE BUNDLE
Document Type and Number:
Japanese Patent JP2006176458
Kind Code:
A
Abstract:

To provide a technique for the resolution of an optically active substance by recognizing a stereochemical structure of a helical molecule (helical compound such as oligopeptide).

The invention provides a method for separating a right-handed or a left-handed spiral molecule from a mixture of the right-handed helical molecule and the left-handed helical molecules. The separation method uses a cyclic compound composed of a cyclic structure part containing two helical supports having the same right-handed or left-handed helical direction and a part placed between the supports and interacting with both terminals of the helical molecule and having a void capable of including the helical molecule. Optical resolution is carried out by forming an associate of the objective helical molecule and the cyclic compound and dissociating the helical molecule from the associate.


Inventors:
Oike, Hideaki
Guo, Yang-ming
Saeki, Naoko
Aida, Takuzo
Application Number:
JP2004000372738
Publication Date:
July 06, 2006
Filing Date:
December 24, 2004
Export Citation:
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Assignee:
JAPAN SCIENCE & TECHNOLOGY AGENCY
International Classes:
C07K7/06; C07B63/02; C07B57/00
Attorney, Agent or Firm:
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