Title:
METHOD FOR TREATING LOCAL TRACHEAL, BRONCHIAL OR ALVEOLAR BLEEDING OR HEMOPTYSIS
Document Type and Number:
Japanese Patent JP2012092131
Kind Code:
A
Abstract:
To provide a method for the local treatment of tracheal, bronchial or alveolar bleeding or hemoptysis and reducing unwanted effects associated with systemic administration of thrombotic agents.
The present invention relates to the intratracheal, intrabronchial or intraalveolar administration to preferably a human inclusive of both adults and children, blood coagulation factors other than thrombin or fibrinogen, preferably activated human factor VII and/or factor XIII via bronchoalveolar lavage using a solution, blind tracheal lavage, or inhalation to stop bleeding from the trachea, bronchi or alveoli, or hemoptysis.
Inventors:
HESLET LARS
UTTENTHAL LARS OTTO
UTTENTHAL LARS OTTO
Application Number:
JP2011280963A
Publication Date:
May 17, 2012
Filing Date:
December 22, 2011
Export Citation:
Assignee:
PHARMAORIGIN APS
International Classes:
A61K38/43; A61K9/12; A61K9/72; A61P7/04; A61P11/00
Domestic Patent References:
| JP2004505016A | 2004-02-19 | |||
| JP2001515460A | 2001-09-18 | |||
| JP2002506697A | 2002-03-05 |
Foreign References:
| WO2003093465A1 | 2003-11-13 | |||
| WO2004091487A2 | 2004-10-28 |
Other References:
JPN5007015444; ＨＥＮＫＥ: ＡＮＮＡＬＳ ＯＦ ＩＮＴＥＲＮＡＬ ＭＥＤＩＣＩＮＥ Ｖ１４０ Ｎ６, 20040316, Ｐ４９３-４９４
JPN5007015445; ＰＡＳＴＯＲＥＳ: ＣＨＥＳＴ Ｖ１２４ Ｎ６, 200312, Ｐ２４００-２４０３
JPN5007015447; ＨＩＣＫＳ: ＢＯＮＥ ＭＡＲＲＯＷ ＴＲＡＮＳＰＬＡＮＴＡＴＩＯＮ Ｖ３０, 2002, Ｐ９７５-９７８
JPN5007015448; ＭＥＩＪＥＲ: ＡＲＣＨＩＶＥＳ ＯＦ ＩＮＴＥＲＮＡＬ ＭＥＤＩＣＩＮＥ Ｖ１６０, 20000724, Ｐ２２１６-２２１７
JPN5007015446; ＢＥＴＥＮＳＬＥＹ: ＡＭＥＲＩＣＡＮ ＪＯＵＲＮＡＬ ＯＦ ＲＥＳＰＩＲＡＴＯＲＹ ＡＮＤ ＣＲＩＴＩＣＡＬ ＣＡＲＥ ＭＥＤＩＣＩＮＥ Ｖ１６６, 2002, Ｐ１２９１-１２９２
JPN5007015444; ＨＥＮＫＥ: ＡＮＮＡＬＳ ＯＦ ＩＮＴＥＲＮＡＬ ＭＥＤＩＣＩＮＥ Ｖ１４０ Ｎ６, 20040316, Ｐ４９３-４９４
JPN5007015445; ＰＡＳＴＯＲＥＳ: ＣＨＥＳＴ Ｖ１２４ Ｎ６, 200312, Ｐ２４００-２４０３
JPN5007015447; ＨＩＣＫＳ: ＢＯＮＥ ＭＡＲＲＯＷ ＴＲＡＮＳＰＬＡＮＴＡＴＩＯＮ Ｖ３０, 2002, Ｐ９７５-９７８
JPN5007015448; ＭＥＩＪＥＲ: ＡＲＣＨＩＶＥＳ ＯＦ ＩＮＴＥＲＮＡＬ ＭＥＤＩＣＩＮＥ Ｖ１６０, 20000724, Ｐ２２１６-２２１７
JPN5007015446; ＢＥＴＥＮＳＬＥＹ: ＡＭＥＲＩＣＡＮ ＪＯＵＲＮＡＬ ＯＦ ＲＥＳＰＩＲＡＴＯＲＹ ＡＮＤ ＣＲＩＴＩＣＡＬ ＣＡＲＥ ＭＥＤＩＣＩＮＥ Ｖ１６６, 2002, Ｐ１２９１-１２９２
JPN5007015445; ＰＡＳＴＯＲＥＳ: ＣＨＥＳＴ Ｖ１２４ Ｎ６, 200312, Ｐ２４００-２４０３
JPN5007015447; ＨＩＣＫＳ: ＢＯＮＥ ＭＡＲＲＯＷ ＴＲＡＮＳＰＬＡＮＴＡＴＩＯＮ Ｖ３０, 2002, Ｐ９７５-９７８
JPN5007015448; ＭＥＩＪＥＲ: ＡＲＣＨＩＶＥＳ ＯＦ ＩＮＴＥＲＮＡＬ ＭＥＤＩＣＩＮＥ Ｖ１６０, 20000724, Ｐ２２１６-２２１７
JPN5007015446; ＢＥＴＥＮＳＬＥＹ: ＡＭＥＲＩＣＡＮ ＪＯＵＲＮＡＬ ＯＦ ＲＥＳＰＩＲＡＴＯＲＹ ＡＮＤ ＣＲＩＴＩＣＡＬ ＣＡＲＥ ＭＥＤＩＣＩＮＥ Ｖ１６６, 2002, Ｐ１２９１-１２９２
JPN5007015444; ＨＥＮＫＥ: ＡＮＮＡＬＳ ＯＦ ＩＮＴＥＲＮＡＬ ＭＥＤＩＣＩＮＥ Ｖ１４０ Ｎ６, 20040316, Ｐ４９３-４９４
JPN5007015445; ＰＡＳＴＯＲＥＳ: ＣＨＥＳＴ Ｖ１２４ Ｎ６, 200312, Ｐ２４００-２４０３
JPN5007015447; ＨＩＣＫＳ: ＢＯＮＥ ＭＡＲＲＯＷ ＴＲＡＮＳＰＬＡＮＴＡＴＩＯＮ Ｖ３０, 2002, Ｐ９７５-９７８
JPN5007015448; ＭＥＩＪＥＲ: ＡＲＣＨＩＶＥＳ ＯＦ ＩＮＴＥＲＮＡＬ ＭＥＤＩＣＩＮＥ Ｖ１６０, 20000724, Ｐ２２１６-２２１７
JPN5007015446; ＢＥＴＥＮＳＬＥＹ: ＡＭＥＲＩＣＡＮ ＪＯＵＲＮＡＬ ＯＦ ＲＥＳＰＩＲＡＴＯＲＹ ＡＮＤ ＣＲＩＴＩＣＡＬ ＣＡＲＥ ＭＥＤＩＣＩＮＥ Ｖ１６６, 2002, Ｐ１２９１-１２９２
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Masahiro Nitta
Kure Hidenori
Nobuhiko Akiyama
Samejima Mutsumi
Masahiro Nitta
Kure Hidenori
Nobuhiko Akiyama