METHOD FOR TREATING STRESS DISORDER USING GLUCOCORTICOID RECEPTOR-SPECIFIC ANTAGONIST

Title:

METHOD FOR TREATING STRESS DISORDER USING GLUCOCORTICOID RECEPTOR-SPECIFIC ANTAGONIST

Document Type and Number:

Japanese Patent JP2009102412

Kind Code:

A

Abstract:

To provide a method for administering a glucocorticoid receptor-specific antagonist to treat a patient diagnosed as stress disorder.

The present invention provides a method for improving a stress disorder symptom in a patient having a normal cortisol level or a lowered cortisol level. The present invention includes administering a therapeutically effective dose of the glucocorticoid receptor antagonist into a patient who can be diagnosed as posttraumatic stress disorder, acute stress disorder, or remarkable stressor-accompanying short-term psychotic disorder. In an embodiment, the method for treating the stress disorder uses the glucocorticoid receptor antagonist containing a steroid skeleton having at least one phenyl-containing portion at the 11-position of the steroid skeleton.

Inventors:

BELANOFF JOSEPH K

Application Number:

JP2009023152A

Publication Date:

May 14, 2009

Filing Date:

February 03, 2009

Export Citation:

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Assignee:

CORCEPT THERAPEUTICS INC

International Classes:

A61K9/10; A61K9/12; A61K45/00; A61K9/20; A61K31/56; A61K31/567; A61K31/569; A61K31/57; A61K31/59; A61P5/46; A61P13/12; A61P25/18; A61P25/24; A61P43/00; C07J1/00

Foreign References:

WO1999017779A1

1999-04-15

Attorney, Agent or Firm:

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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