Title:
METHOD FOR TREATMENT OF DISEASE USING MALONYL-COA DECARBOXYLASE INHIBITOR
Document Type and Number:
Japanese Patent JP2008001719
Kind Code:
A
Abstract:
To provide methods for the prophylaxis, management and treatment of certain diseases modulated by the inhibition of the enzyme malonyl-coenzyme A decarboxylase (malonyl-CoA decarboxylase, MCD).
The invention relates to methods for the prophylaxis, management and treatment of cardiovascular diseases, diabetes, acidosis, cancers, and obesity through the administration of a composition containing a compound of formula (I) as an active ingredient. The present invention also includes within its scope the novel process for the preparation of certain compounds.
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Inventors:
ARRHENIUS THOMAS
CHEN MI
CHENG JIE FEI
HARAMURA MASAYUKI
HUANG YUJIN
NADZAN ALEX
TITH SOVOUTHY
WALLACE DAVID
ZHANG LIN
BROWN STEVE
HARMON CHARLES
CHEN MI
CHENG JIE FEI
HARAMURA MASAYUKI
HUANG YUJIN
NADZAN ALEX
TITH SOVOUTHY
WALLACE DAVID
ZHANG LIN
BROWN STEVE
HARMON CHARLES
Application Number:
JP2007227557A
Publication Date:
January 10, 2008
Filing Date:
September 03, 2007
Export Citation:
Assignee:
CHUGAI PHARMACEUTICAL CO LTD
International Classes:
A61K31/167; C07D295/18; A61K31/16; A61K31/165; A61K31/166; A61K31/17; A61K31/175; A61K31/18; A61K31/195; A61K31/197; A61K31/198; A61K31/21; A61K31/215; A61K31/216; A61K31/22; A61K31/221; A61K31/223; A61K31/27; A61K31/275; A61K31/277; A61K31/341; A61K31/381; A61K31/40; A61K31/404; A61K31/41; A61K31/415; A61K31/416; A61K31/4164; A61K31/4172; A61K31/4178; A61K31/4188; A61K31/4196; A61K31/42; A61K31/421; A61K31/4245; A61K31/44; A61K31/4402; A61K31/4409; A61K31/4439; A61K31/444; A61K31/445; A61K31/4453; A61K31/451; A61K31/455; A61K31/495; A61K31/498; A61K31/5375; A61K31/5377; A61P3/00; A61P3/04; A61P3/10; A61P3/12; A61P9/00; A61P9/04; A61P9/10; A61P35/00; A61P43/00; C07C33/46; C07C33/48; C07C215/24; C07C233/22; C07C257/22; C07C279/18; C07C307/10; C07C323/14; C07C335/18; C07D209/42; C07D211/14; C07D211/22; C07D213/40; C07D213/56; C07D213/70; C07D213/75; C07D213/81; C07D213/82; C07D231/06; C07D231/12; C07D231/14; C07D231/38; C07D231/40; C07D233/54; C07D233/64; C07D233/84; C07D233/90; C07D239/42; C07D241/24; C07D257/04; C07D261/04; C07D261/08; C07D261/14; C07D261/18; C07D263/34; C07D271/06; C07D277/46; C07D277/48; C07D277/52; C07D285/135; C07D295/13; C07D295/194; C07D295/21; C07D295/215; C07D295/22; C07D295/28; C07D307/46; C07D307/52; C07D307/68; C07D333/24; C07D401/04; C07D401/12; C07D403/12; C07D405/12; C07D409/04; C07D413/06; C07D413/12; C07D417/12; C07D417/14; C07D487/08; C07D498/08; C07F9/24; C07F9/40; C07F9/6539; C07D285/12
Foreign References:
WO2000054759A2 | 2000-09-21 | |||
WO2001003705A1 | 2001-01-18 |
Attorney, Agent or Firm:
Hatsushi Shimizu