Title:
フェニルアミジン誘導体を含有する医薬組成物および抗真菌剤を組み合わせて使用する方法
Document Type and Number:
Japanese Patent JP5132569
Kind Code:
B2
Abstract:
A pharmaceutical composition comprising a phenylamidine derivative or a salt thereof, represented by a general formula,
wherein R 1 and R 2 may be same or different, and represent an optionally substituted C 3-4 alkyl group; and one or more agents selected from azole antifungal agents, polyene antifungal agents, candin antifungal agents and fluoropyrimidine antifungal agents, and a method for combination use of the phenylamidine derivative or a salt thereof and the agents are useful for treating fungal infections caused by a fungal pathogen.
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Inventors:
Hiroshi Nishikawa
Application Number:
JP2008538673A
Publication Date:
January 30, 2013
Filing Date:
October 03, 2007
Export Citation:
Assignee:
Toyama Chemical Co., Ltd.
International Classes:
A61K31/445; A61K31/4196; A61K31/496; A61K31/506; A61K31/661; A61K31/7048; A61K38/00; A61K45/00; A61P31/10; A61P43/00
Foreign References:
| WO2006003881A1 | 2006-01-12 |
Other References:
JPN6007005936; 二木芳人 外: 'Ｍｉｃａｆｕｎｇｉｎとａｍｐｈｏｔｅｒｉｃｉｎ Ｂ， ｉｔｒａｃｏｎａｚｏｌｅおよびｆｌｕｃｏｎａｚｏｌｅとの併用効果' 日本化学療法学会雑誌 Ｖｏｌ．５０， Ｎｏ．Ｓｕｐｐｌｅｍｅｎｔ-１, 2002, ｐ．５８-６７
Attorney, Agent or Firm:
Asamura patent office
Hideto Asamura
Hajime Asamura
Shinmura Morio
Naganuma Akio
Yukihiro Ikeda
Kajiwara Saiko
Kanamori Koji
Yuko Nagase
Katsunori Ando
Hideto Asamura
Hajime Asamura
Shinmura Morio
Naganuma Akio
Yukihiro Ikeda
Kajiwara Saiko
Kanamori Koji
Yuko Nagase
Katsunori Ando