Title:
修飾特異的バインダーを使用することによる分析物を分析するための方法
Document Type and Number:
Japanese Patent JP6840541
Kind Code:
B2
Abstract:
Method, kit and composition for analyzing analytes for modifications using modification site specific antibodies to bind an analyte with his specific modification sites of interest to different dyes simultaneously with an antibody which is specific to the non-modificated analyte binding to another dye to determine the concentration of the analyte for quantification of the modified analyte in the identical sample.
Inventors:
Yarlink, Frank
Bratt, Fried Helm
Kur, Jessica
Bratt, Fried Helm
Kur, Jessica
Application Number:
JP2016559913A
Publication Date:
March 10, 2021
Filing Date:
February 27, 2015
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
G01N33/53; G01N33/543; G01N33/573; G01N33/574
Domestic Patent References:
| JP2009501516A | ||||
| JP2007530024A |
Other References:
RANDY J、他4名,Cellular Analysis Using MILLIPLEX MAP TGF-β Signaling Pathway Panel,millipore,2012年
RANDY J、他4名,Abstract 1237: TGF-β signaling pathway analysis using MILLIPLEX MAP TGF-β multiplex panel,Proceedings:AACR 103rd Annual Meeting 2012,2012年,DOI:10.1158/1538-7445.AM2012-1237 Published April 2012
Bernsteel DJ、他2名,In vitro protein kinase activity measurement by flow cytometry.,Anal Biochem.,2008年12月 8日,Vol.383,No.2 ,Page.180-185,doi: 10.1016/j.ab.2008.08.026. Epub 2008 Sep
SA Dunbar、他1名,Introduction to Luminex xMAP. Technology and Applications for. Biological Analysis in China.,asiabiotech,2010年10月,https://www.asiabiotech.com/14/1410/0026_0030.pdf
Human RTK Phosphorylation. Antibody Array G-series 1. For Simultaneously Detecting the Relative Level of Tyrosin. Phosphorylation of Human Receptor Tyrosine Kinases (RTKs).,RayBio User Manual.,2008年
RANDY J、他4名,Abstract 1237: TGF-β signaling pathway analysis using MILLIPLEX MAP TGF-β multiplex panel,Proceedings:AACR 103rd Annual Meeting 2012,2012年,DOI:10.1158/1538-7445.AM2012-1237 Published April 2012
Bernsteel DJ、他2名,In vitro protein kinase activity measurement by flow cytometry.,Anal Biochem.,2008年12月 8日,Vol.383,No.2 ,Page.180-185,doi: 10.1016/j.ab.2008.08.026. Epub 2008 Sep
SA Dunbar、他1名,Introduction to Luminex xMAP. Technology and Applications for. Biological Analysis in China.,asiabiotech,2010年10月,https://www.asiabiotech.com/14/1410/0026_0030.pdf
Human RTK Phosphorylation. Antibody Array G-series 1. For Simultaneously Detecting the Relative Level of Tyrosin. Phosphorylation of Human Receptor Tyrosine Kinases (RTKs).,RayBio User Manual.,2008年
Attorney, Agent or Firm:
Kiyoji Kuzuwa
Kenichi Sugie
Kenichi Sugie