Title:
クッシング症候群についての処置を診断および評価するための方法
Document Type and Number:
Japanese Patent JP6893264
Kind Code:
B2
Abstract:
Methods are provided for assessing a clinical response to a glucocorticoid receptor antagonist (GRA) in a human subject and for diagnosing Cushing's syndrome.
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Inventors:
Joseph K. Bellanov
Hazel hunt
John Francis Unit
Andreas G. Moraitis
Hazel hunt
John Francis Unit
Andreas G. Moraitis
Application Number:
JP2020024990A
Publication Date:
June 23, 2021
Filing Date:
February 18, 2020
Export Citation:
Assignee:
Cocept Therapeutics, Incorporated
International Classes:
G01N33/68; A61K31/03; A61K31/07; A61K31/4164; A61K31/4188; A61K31/444; A61K31/451; A61K31/48; A61K31/496; A61K31/4985; A61K31/52; A61K31/567; A61K38/31; A61K45/00; A61P5/38; A61P7/00; C12N15/12; C12Q1/02; C12Q1/533; C12Q1/6813; G01N33/50
Domestic Patent References:
| JP2013090761A |
Foreign References:
| WO2013039916A1 | ||||
| US20120094945 | ||||
| US20120039812 |
Other References:
LEE Richard S. et al.,A measure of glucocorticoid load provided by DNA methylation of Fkbp5 in mice,Psychopharmacology,2011年,Vol.218, No.1,pp.303-312
VERMEER Harry et al.,Glucocorticoid-Induced Increase in Lymphocytic FKBP51 Messenger Ribonucleic Acid Expression: A Poten,The Journal of Clinical Endocrinology & Metabolism,2003年,Vol.88, No.1,pp.277-284
VERMEER Harry et al.,Glucocorticoid-Induced Increase in Lymphocytic FKBP51 Messenger Ribonucleic Acid Expression: A Poten,The Journal of Clinical Endocrinology & Metabolism,2003年,Vol.88, No.1,pp.277-284
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita