Title:
ナトリウム/カルシウム交換輸送体の活性を調節する化合物の同定方法
Document Type and Number:
Japanese Patent JP5331339
Kind Code:
B2
Abstract:
The invention refers to a cell free assay for determining the activity of a Na+/Ca2+ exchanger (NCX) protein by means of a cell free electrophysiological sensor chip, a kit of parts comprising the sensor chip with a NCX protein as well as the manufacturing and use of the kit of parts.
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Inventors:
Henning Forelt
Sven Gebel
Bella Kellety
Wolfgang Derner
Sven Gebel
Bella Kellety
Wolfgang Derner
Application Number:
JP2007526352A
Publication Date:
October 30, 2013
Filing Date:
August 10, 2005
Export Citation:
Assignee:
Sanofi-Aventis Deutschland Gesellschaft Mitt Beschlenktel Haftung
International Classes:
G01N33/68; G01N27/327; G01N27/333; G01N33/483; G01N33/50; G01N33/543
Foreign References:
| US20040106126 | ||||
| WO2002074983A1 |
Other References:
Bruce Alberts,細胞の分子生物学 第3版,日本,株式会社 ニュートンプレス,2001年12月10日,Vol.3,P.508
A. Eisenrauch,Electrical Currents Generated by a Partially Purified Na/Ca Exchanger from Lobster Muscle Reconstituted into Liposomes and Adsorbed on Black Lipid Membranes:Activation by Photolysis of Caged Ca2+,Jounal of Membrane Biology,米国,Springer-Verlag New York Inc.,1995年 5月,Vol.145/No.2,151-164
木村純子,Na+-Ca2+交換輸送体の薬理学的修飾,心臓,日本,日本心臓財団,2002年,Vol.34/No.4,306-312
A. Eisenrauch,Electrical Currents Generated by a Partially Purified Na/Ca Exchanger from Lobster Muscle Reconstituted into Liposomes and Adsorbed on Black Lipid Membranes:Activation by Photolysis of Caged Ca2+,Jounal of Membrane Biology,米国,Springer-Verlag New York Inc.,1995年 5月,Vol.145/No.2,151-164
木村純子,Na+-Ca2+交換輸送体の薬理学的修飾,心臓,日本,日本心臓財団,2002年,Vol.34/No.4,306-312
Attorney, Agent or Firm:
Chika Takagi
Junji Yuda
Shoji Miwa
Noriyuki Takebayashi
Shinsuke Arai
Hiroki Inuyama
Junji Yuda
Shoji Miwa
Noriyuki Takebayashi
Shinsuke Arai
Hiroki Inuyama
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