Title:
リン定量化のための方法
Document Type and Number:
Japanese Patent JP4159987
Kind Code:
B2
Abstract:
A method of detecting and measuring phosphorus in samples is disclosed. The measurement of phosphorylation is made with an inductively coupled plasma mass spectrometer (ICP-MS), coupled to a reactive collision cell. The reactive collision cell is employed to ensure interference-free detection of phosphorus ions, by the formation of product ions with a different mass to charge ratio. Accurate measurement of phosphorylation in samples is important in proteomics.
Inventors:
Dmitry Earl Bandura
Vladimir I Baranov
Scott Dee Tanner
Vladimir I Baranov
Scott Dee Tanner
Application Number:
JP2003514581A
Publication Date:
October 01, 2008
Filing Date:
July 17, 2002
Export Citation:
Assignee:
MDS INC., Doing Business As MDS SCIEX
International Classes:
G01N27/62; G01N30/72; G01N33/00; G01N33/68; H01J49/10; H01J49/16
Other References:
WIND M,“Protein Phosphorylation Degree: Determination by Capillary Liquid Chromatography and Inductively Coupled Plasma Mass Spectrometry”,ANALYTICAL CHEMISTRY,2001年 7月 1日,Vol.73, No.13,pp.3006-3010
TANNER S D,“A Dynamic Reaction Cell for Inductively Coupled Plasma Mass Spectrometry(ICP-DRC-MS).II.Reduction of Interferences Produced Within the Cell”,JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY,米国,ELSEVIER SCIENCE INC,1999年11月,Vol.10, No.11,pp.1083-1094
TANNER S D,“A Dynamic Reaction Cell for Inductively Coupled Plasma Mass Spectrometry(ICP-DRC-MS).II.Reduction of Interferences Produced Within the Cell”,JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY,米国,ELSEVIER SCIENCE INC,1999年11月,Vol.10, No.11,pp.1083-1094
Attorney, Agent or Firm:
Kenichi Takasaki