METHODS AND COMPOSITIONS FOR INHIBITING, PREVENTING OR REDUCING TUMOR CELL GROWTH IN PATIENTS RESISTANT TO ANTINEOPLASTIC EFFECTS OF ANTIESTROGEN THERAPY

Title:

METHODS AND COMPOSITIONS FOR INHIBITING, PREVENTING OR REDUCING TUMOR CELL GROWTH IN PATIENTS RESISTANT TO ANTINEOPLASTIC EFFECTS OF ANTIESTROGEN THERAPY

Document Type and Number:

Japanese Patent JP2015227369

Kind Code:

A

Abstract:

PROBLEM TO BE SOLVED: To provide pharmaceuticals for treating cancer.SOLUTION: There is provided the use of an antiestrogen compound and a GP88 antagonist in production of pharmaceuticals for treating antiestrogen resistant cancer.

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Inventors:

SERRERO GINETTE

Application Number:

JP2015156532A

Publication Date:

December 17, 2015

Filing Date:

August 07, 2015

Export Citation:

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Assignee:

A & G PHARMACEUTICALS INC

International Classes:

A61K45/00; A61K45/06; A61K31/138; A61K31/4535; A61K31/7088; A61K39/395; A61K48/00; A61P15/00; A61P35/00; A61P43/00; C07K14/475; C07K16/22; C07K16/30; C12N15/09; C12Q1/02; C12Q1/68; G01N33/574; G01N37/00; A61K38/00

Other References:

JPN6010045170; Ｐｒｏｃ．Ｎａｔｌ．Ａｃａｄ．Ｓｃｉ．ＵＳＡＶｏｌ．９８，Ｎｏ．１, 2001, ｐ１４２-１４７
JPN6010045172; Ｐｒｏｃ．Ｎａｔｌ．Ａｃａｄ．Ｓｃｉ．ＵＳＡＶｏｌ．９７，Ｎｏ．８, 2000, ｐ３９９３-３９９８
JPN6010045177; Ｃａｎｃｅｒ　ＲｅｓｅａｒｃｈＶｏｌ．６０，Ｎｏ．５, 2000, ｐ１３５３-１３６０
JPN6010045179; Ｐｒｏｃ．Ｎａｔｌ．Ａｃａｄ．Ｓｃｉ．ＵＳＡＶｏｌ．９５，Ｎｏ．２４, 1998, ｐ１４２０２-１４２０７
JPN6010045168; Ｂｉｏｃｈｅｍｉｃａｌ　ａｎｄ　Ｂｉｏｐｈｙｓｉｃａｌ　Ｒｅｓｅａｒｃｈ　ＣｏｍｍｕｎｉｃａｔｉｏｎＶｏｌ．２５６，Ｎｏ．１, 1999, ｐ２０４-２０７

Attorney, Agent or Firm:

Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka

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