Title:
抗体コード配列をセーフハーバー遺伝子座に挿入するための方法および組成物
Document Type and Number:
Japanese Patent JP2022527809
Kind Code:
A
Abstract:
広域中和抗体などの抗原結合タンパク質のコード配列をインビボで動物のアルブミン遺伝子座などのセーフハーバー遺伝子座に組み込むための、方法および組成物が提供される。【選択図】図１
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Inventors:
Hartford, Sae Yamamoto
Wang, Chen
Gon, Guo Chun
Karatsuos, Christos
Zambrowitz, Brian
Janco Poros, George Dee.
Wang, Chen
Gon, Guo Chun
Karatsuos, Christos
Zambrowitz, Brian
Janco Poros, George Dee.
Application Number:
JP2021558841A
Publication Date:
June 06, 2022
Filing Date:
April 02, 2020
Export Citation:
Assignee:
REGENERON PHARMACEUTICALS, INC.
International Classes:
C12N15/09; A01K67/027; A61K39/00; A61K39/002; A61K39/12; A61K39/145; A61K39/395; A61K48/00; A61P31/00; A61P31/12; A61P31/14; A61P31/16; A61P35/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/13; C12N15/864
Attorney, Agent or Firm:
Shusaku Yamamoto
Morishita Natsuki
Morishita Natsuki