Title:
BCH-189関連化合物の合成のための方法および組成物
Document Type and Number:
Japanese Patent JP4496377
Kind Code:
B2
Abstract:
The present invention relates to a method of preparing BCH-189 and various analogues of BCH-189 from inexpensive precursors with the option of introducing functionality as needed. This synthetic route allows the stereoselective preparation of the biologically active isomer of these compounds, ²-BCH-189 and related compounds. Furthermore, the stereochemistry at the nucleoside 4'-position can be controlled to produce enantiomerically-enriched ²-BCH-189 and its analogues.
Inventors:
Dennis Sea. Riotta
Woo-Fly Choi
Woo-Fly Choi
Application Number:
JP2006033782A
Publication Date:
July 07, 2010
Filing Date:
February 10, 2006
Export Citation:
Assignee:
Emory University
International Classes:
A61K31/505; C12P41/00; A61K31/00; A61K31/39; A61K31/513; A61K31/695; A61K31/7064; A61K31/7068; A61P31/12; A61P31/18; C07D239/02; C07D327/04; C07D405/04; C07D411/04; C07D451/00; C07F7/18; C07H19/06; C07H19/10; C12P19/38; A61K; C07D
Domestic Patent References:
| JP37282A |
Other References:
Abstracts of the 5th International Conference on AIDS,1989,p.515,552
Chemical&Engineering News,June 26,1989,p.7-16
Chemical&Engineering News,June 26,1989,p.7-16
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura