Title:
神経変性を治療するための方法及び組成物
Document Type and Number:
Japanese Patent JP6673966
Kind Code:
B2
Abstract:
Disclosed herein are methods and compositions for the use of marrow adherent stem cells and their descendents; e.g., bone marrow-derived neural regenerating cells; for provision of angiogenic factors to cells. In certain embodiments, provision of angiogenic factors to sites of neural degeneration stimulates growth and/or survival of host neurons.
Inventors:
Keita Mori
Bourne, Martha Dee.
Tate, Ciara
Eisman, Irina
Grabaski, Alexandra
Villag, Tamas
Bourne, Martha Dee.
Tate, Ciara
Eisman, Irina
Grabaski, Alexandra
Villag, Tamas
Application Number:
JP2018070714A
Publication Date:
April 01, 2020
Filing Date:
April 02, 2018
Export Citation:
Assignee:
Sanbio, Incorporated
International Classes:
A61K35/28; A61P9/00; A61P21/00; A61P25/00; A61P25/02; A61P25/16; A61P25/28; A61P43/00; C12N5/077; C12N5/079; C12N5/10; A61K35/12
Domestic Patent References:
| JP2004256428A | ||||
| JP8502652A | ||||
| JP2003144155A |
Foreign References:
| WO2006096640A1 | ||||
| WO2003066856A1 |
Other References:
J. Clin. Invest. (2004) Vol.113, pp.1701-1710
日薬理誌 (2002) Vol.119, pp.79-88
日本脊髄障害医学会雑誌 (2007) Vol.20, No.1, pp.176-177
日本脳神経外科学会総会抄録集 (2007) Vol.65, p.2P-315
Exp. Opin. Biol. Ther. (2005) Vol.5, No.4, pp.427-435
Davies A.M., "Trophic Support", Encyclopedia of Life Science (2001), pp.1-4
日薬理誌 (2002) Vol.119, pp.79-88
日本脊髄障害医学会雑誌 (2007) Vol.20, No.1, pp.176-177
日本脳神経外科学会総会抄録集 (2007) Vol.65, p.2P-315
Exp. Opin. Biol. Ther. (2005) Vol.5, No.4, pp.427-435
Davies A.M., "Trophic Support", Encyclopedia of Life Science (2001), pp.1-4
Attorney, Agent or Firm:
Atsushi Aoki
Shinji Mitsuhashi
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei
Kazumi Nakamura
Shinji Mitsuhashi
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei
Kazumi Nakamura