Title:
Methods for controlling blood pressure and reducing dyspnea in heart failure
Document Type and Number:
Japanese Patent JP6329957
Kind Code:
B2
Abstract:
Methods for controlling, maintaining, or reducing blood pressure, and/or for treating, preventing, or alleviating symptoms such as dyspnea, in a patient suffering from or susceptible to acute heart failure. The methods involve the administration of an effective amount of a pharmaceutical composition comprising a short acting dihydropyridine compound such as clevidipine. The pharmaceutical composition may be administered at an initial dose, and if blood pressure is not controlled or maintained within a target blood pressure range or reduced to within a target blood pressure range, the initial dose may be titrated to achieve a blood pressure within the target blood pressure range. The patient may have a systolic blood pressure of about 120 mmHg or above.
Inventors:
Spindler, Edward Sea. Junior
Itri, Loretta Em.
Williams, Gregory Charles
Fu, Min-i
Itri, Loretta Em.
Williams, Gregory Charles
Fu, Min-i
Application Number:
JP2015539879A
Publication Date:
May 23, 2018
Filing Date:
October 26, 2013
Export Citation:
Assignee:
Chiesie Pharmaceutic S.P.A.
International Classes:
A61K31/4422; A61P9/04; A61P9/12; A61P11/00
Foreign References:
| WO2012135617A1 | ||||
| WO2012051116A1 |
Other References:
ClinicalTrials.govに登録された臨床試験「NCT00803634」について2012年6月6日付けで更新された情報[オンライン],2012年 6月 6日,URL,https://clinicaltrials.gov/archive/NCT00803634/2012_06_06
[ダイジェスト版]急性心不全治療ガイドライン(2011年改訂版)[オンライン],2011年,p.16,17,18(表17),41(図17),URL,http://www.j-circ.or.jp/guideline/pdf/JCS2011_izumi_d.pdf
[ダイジェスト版]急性心不全治療ガイドライン(2011年改訂版)[オンライン],2011年,p.16,17,18(表17),41(図17),URL,http://www.j-circ.or.jp/guideline/pdf/JCS2011_izumi_d.pdf
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto