Title:
METHOD AND SYSTEM FOR IMPROVING DISEASE DIAGNOSIS USING MEASURED ANALYTES
Document Type and Number:
Japanese Patent JP2023156388
Kind Code:
A
Abstract:
To provide methods of improving accuracy of disease diagnosis and associated diagnostic tests involving a correlation of measured analytes with binary outcomes.SOLUTION: A computer-implemented method of diagnosing a disease is provided, comprising steps of: determining concentration of at least three biomarkers in a blind sample collected from a subject; selecting one or more meta-variables associated with the subject; transforming the concentration of the biomarkers as a function of one or more population distribution characteristics and the one or more meta-variables to compute pseudo-concentration representing each biomarker; comparing the pseudo-concentration with a training set model of pseudo-concentration determined for members of population who are known either to have or not have the disease; and determining whether the comparison indicates that the subject has the disease.SELECTED DRAWING: Figure 1
Inventors:
GALINA KRASIK
MOHSEN MAREFAT
KEITH LINGENFELTER
MOHSEN MAREFAT
KEITH LINGENFELTER
Application Number:
JP2023126095A
Publication Date:
October 24, 2023
Filing Date:
August 02, 2023
Export Citation:
Assignee:
OTRACES INC
International Classes:
G16H10/40; G01N33/68
Attorney, Agent or Firm:
Norito Yamao
Norifumi Tomita
Fumio Inai
Manami Sasakura
Norifumi Tomita
Fumio Inai
Manami Sasakura
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