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Title:
血液および組織中の細菌を免疫学的に検出する方法およびキット
Document Type and Number:
Japanese Patent JP5777877
Kind Code:
B2
Abstract:
The invention provides methods for screening for the presence of a clinically relevant amount of bacteria in donor blood or a blood product from a donor mammal, particularly blood or a blood product that will be transferred from the donor mammal to a recipient mammal. The method comprises contacting a sample of the donor blood or a blood product with a set of binding agents that comprises binding agents that specifically bind to Gram-negative bacterial antigen and/or binding agents that specifically bind to Gram-positive bacterial antigen, and determining binding of the set of binding agents to the sample, wherein binding indicates the presence of a clinically relevant amount of Gram-positive bacteria and/or Gram-negative bacteria in the donor blood or blood product and no binding indicates the absence of a clinically relevant amount of Gram-positive bacteria and/or Gram-negative bacteria in the donor blood or blood product. The invention further provides methods and kits for screening for the presence of a clinically relevant amount of Gram-positive bacteria, Gram-negative bacteria, or both Gram-positive and Gram-negative bacteria in a donor tissue by screening the fluid in which the donor tissue is stored.

Inventors:
Good Now, Timothy Tea.
Application Number:
JP2010274071A
Publication Date:
September 09, 2015
Filing Date:
December 08, 2010
Export Citation:
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Assignee:
Velax Biomedical, Inc.
International Classes:
A61K35/14; G01N33/569; A61P7/08; C12Q1/00; G01N33/533; G01N33/534; G01N33/535; G01N33/543
Domestic Patent References:
JP62228295A
JP60259966A
Foreign References:
WO1996040251A1
Attorney, Agent or Firm:
Kiyoji Kuzuwa