METHODS, PHARMACEUTICAL COMPOSITIONS AND KITS FOR USE IN TREATMENT OF ADULT T-CELL LEUKEMIA/LYMPHOMA

Title:

METHODS, PHARMACEUTICAL COMPOSITIONS AND KITS FOR USE IN TREATMENT OF ADULT T-CELL LEUKEMIA/LYMPHOMA

Document Type and Number:

Japanese Patent JP2015199762

Kind Code:

A

Abstract:

PROBLEM TO BE SOLVED: To provide methods, pharmaceutical compositions and kits for the use in the treatment of Adult T-cell leukemia/lymphoma, which exhibits a remarkably high response rate with moderate side effects.SOLUTION: The invention provides a pharmaceutical composition in which interferon, such as interferon α, an arsenic compound selected from arsenic, arsenic trioxide (As2O3), melarsoprol, arsenic sulfur derivatives, and the like, and a reverse transcriptase inhibitor, such as zidovudine are combined.

Inventors:

HUGUES DE THE
ALI BAZARBACHI
OLIVIER HERMINE

Application Number:

JP2015121493A

Publication Date:

November 12, 2015

Filing Date:

June 16, 2015

Export Citation:

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Assignee:

INST NAT SANTE RECH MED
AMERICAN UNIV OF BEIRUT

International Classes:

A61K31/555; A61K31/7072; A61K33/36; A61K38/21; A61K45/00; A61P31/18; A61P35/00; A61P35/02; A61P43/00

Other References:

JPN6014007013; Ｋｃｈｏｕｒ，Ｇ．，ｅｔ　ａｌ．: '"Ｐｈａｓｅ　２　ｓｔｕｄｙ　ｏｆ　ｔｈｅ　ｅｆｆｉｃａｃｙ　ａｎｄ　ｓａｆｅｔｙ　ｏｆ　ｔｈｅ　ｃｏｍｂｉｎａｔｉｏｎ　ｏｆ　ａｒｓｅｎｉｃ　ｔｒｉｏｘｉｄｅ，　ｉｎｔｅｒｆｅｒｏｎ　ａｌｐｈａ，' ＢｌｏｏｄＶｏｌ．１１３，Ｎｏ．２６, 20090625, Ｐ．６５２８-６５３２
JPN6014007014; Ｂａｚａｒｂａｃｈｉ，Ａ．，ｅｔ　ａｌ．: '"Ｔｈｅ　Ｃｏｍｂｉｎａｔｉｏｎ　ｏｆ　Ａｒｓｅｎｉｃ　Ｔｒｉｏｘｉｄｅ　ａｎｄ　Ｉｎｔｅｒｆｅｒｏｎ-Ａｌｐｈａ　Ｅｒａｄｉｃａｔｅｓ　Ｌｅｕｋｅｍｉａ　Ｉｎｉｔｉａｔｉｎｇ　Ｃｅｌｌｓ　ｉｎ　ＴＡ' Ｂｌｏｏｄ　（ＡＳＨ　Ａｎｎｕａｌ　Ｍｅｅｔｉｎｇ　Ａｂｓｔｒａｃｔｓ）Ｖｏｌ．１１４，Ｎｏ．２２, 20091120
JPN6014007015; 志々目光希子　外７名: '"６８．　亜ヒ酸はＡＴＬにも有効か？　自験例３例のまとめ"' 日本リンパ網内系学会会誌Ｖｏｌ．４３，Ｓｕｐｐｌ．, 20030620, Ｐ．７８, 日本リンパ網内系学会

Attorney, Agent or Firm:

Patent business corporation Tsukuni

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