Title:
多能性幹細胞の分化能の予測方法及びそのための試薬
Document Type and Number:
Japanese Patent JP6736772
Kind Code:
B2
Abstract:
Provided is a marker capable of predicting differentiation resistance of a pluripotent stem cell while it is in an undifferentiated state, and a method for rapidly evaluating differentiation potential of the pluripotent stem cell by using expression of the marker as an index. Also provided is a means for searching for culture conditions suitable for maintaining the differentiation potential of a pluripotent stem cell by using expression of the differentiation resistance prediction marker as an index. Further provided is a method for evaluating a medium for a pluripotent stem cell by using expression of the differentiation resistance prediction marker as an index.A method for predicting a differentiation potential of a pluripotent stem cell comprising measuring an expression level of CHD7of the human pluripotent stem cell. A method for evaluating a medium for a human pluripotent stem cell comprising measuring an expression level of CHD7 of the pluripotent stem cell.
Inventors:
Kawamata Shin
Takako Yamamoto
Chiemi Takenaka
Takako Yamamoto
Chiemi Takenaka
Application Number:
JP2019525331A
Publication Date:
August 05, 2020
Filing Date:
June 04, 2018
Export Citation:
Assignee:
Kobe Medical Industry City Promotion Organization
International Classes:
C12N15/09; C12N5/0735; C12N5/10; C12Q1/6851
Domestic Patent References:
| JP2014523735A |
Foreign References:
| WO2012115270A1 |
Other References:
PLoS Genet.,2010年 7月15日,Vol.6, No.7, e1001023,p.1-15
Attorney, Agent or Firm:
Takashima Ichi
Mitsunori Kamata
Kyoko Doi
Yaeko Tamura
Hirofumi Toma
Atsuko Akai
Tomiya Tozaki
Yosuke Ito
Takayuki Ohara
Mitsunori Kamata
Kyoko Doi
Yaeko Tamura
Hirofumi Toma
Atsuko Akai
Tomiya Tozaki
Yosuke Ito
Takayuki Ohara