Title:
METHODS FOR PROTEIN LIGATION AND USES THEREOF
Document Type and Number:
Japanese Patent JP2023016842
Kind Code:
A
Abstract:
To provide a protein complex.SOLUTION: The invention relates to protein ligation technologies, purified or recombinant peptides, methods for making peptides and proteins with covalent bonds including reversible covalent bonds such as reversible intermolecular covalent bonds, and uses thereof. In particular, this invention relates to intermolecular ester bonds, particularly reversible ester bonds between the hydroxyl and amide groups of amino acid side chains present in recombinant chimeric peptides and proteins and the use of such peptides and proteins in protein engineering, for example in the preparation of multimeric protein complexes, including functionalised multimeric protein complexes.SELECTED DRAWING: Figure 20
Inventors:
Christopher John Squire
edward neil baker
Paul Gary Young
Yuliana Yossaat Madhya
edward neil baker
Paul Gary Young
Yuliana Yossaat Madhya
Application Number:
JP2022181857A
Publication Date:
February 02, 2023
Filing Date:
November 14, 2022
Export Citation:
Assignee:
Auckland Uniservices Limited
International Classes:
C07K1/00; C07K1/12; C07K14/00; C07K19/00; C12P21/02
Attorney, Agent or Firm:
Aoki Atsushi
Shinji Mihashi
Youichi Watanabe
Nakajima Masaru
Ryotaro Takei
Michiko Uehara
Shinji Mihashi
Youichi Watanabe
Nakajima Masaru
Ryotaro Takei
Michiko Uehara
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