Title:
循環結晶化プロセスおよび結晶化デバイスによってラセミ化合物形成キラル物質を分離するための方法
Document Type and Number:
Japanese Patent JP5513621
Kind Code:
B2
Abstract:
The invention concerns a method for separating a racemic compound-forming chiral substance by a cyclic crystallization process which is conducted in at least one first crystallization unit (10) and in at least one second crystallization unit (18), wherein in a first process cycle an enantiomer is crystallized in the first crystallization unit (10) and a racemic compound is crystallized in the second crystallization unit (18),
wherein in a second process cycle the enantiomer is crystallized in the second crystallization unit (18) and the racemic compound is crystallized in the first crystallization unit (10), wherein during each process cycle in at least one process sub-step (BC, FG) a mother liquor (12) being contained in the first crystallization unit (10) is mutually exchanged with a mother liquor (20) being contained in the second crystallization unit (18). An auto-seeding process sub-step is applied at the beginning of a process cycle.
Inventors:
Lorenz, Haike
Polanski, Daniel
Curcas, linz
Seidel-Morgen-Stern, Andreas
Polanski, Daniel
Curcas, linz
Seidel-Morgen-Stern, Andreas
Application Number:
JP2012527298A
Publication Date:
June 04, 2014
Filing Date:
August 31, 2010
Export Citation:
Assignee:
Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
International Classes:
C07C51/43; B01D9/02; C07C59/50; C07B57/00
Domestic Patent References:
| JP9506861A | ||||
| JP2006511588A | ||||
| JP9066202A | ||||
| JP55115846A | ||||
| JP6340599A | ||||
| JP61148156A |
Foreign References:
| GB1273278A | ||||
| US3266871 | ||||
| US20080207944 |
Attorney, Agent or Firm:
Patent Business Corporation Unias International Patent Office