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Title:
自閉症スペクトラム障害および関連する症候を治療するための方法
Document Type and Number:
Japanese Patent JP7273082
Kind Code:
B2
Abstract:
The present disclosure relates to compositions and methods for treating autism spectrum disorder (ASD) by restoring an ASD patient's gut microbiota. These methods can be used with ASD patient with or without ongoing gastrointestinal symptoms. Provided here is a method for ASD treatment in a subject in need thereof comprising or consisting essentially of administering a therapeutic composition comprising a fecal microbe or a fecal microbiota preparation to the subject. Also provided here is a method comprises administering an antibiotic to a human subject; subjecting the human subject to a bowel cleanse; and administering purified fecal microbiota to the human subject. Further provided are evaluation and quantitative characterization of patient symptom improvements upon treatment described here.

Inventors:
James Adams
Rosa Krajmarnik-Brown
Deok-Ku
Michael jay sudowski
Alexander Coults
Thomas Jay Borody
Application Number:
JP2021043502A
Publication Date:
May 12, 2023
Filing Date:
March 17, 2021
Export Citation:
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Assignee:
Arizona Board of Regents On Behalf of Arizona State University
Regents of the University of Minnesota
Finch Therapeutics Holdings LLC
International Classes:
A61K35/741; A61K9/14; A61K9/19; A61K9/20; A61K9/48; A61K9/50; A61K35/747; A61K47/10; A61K47/18; A61K47/20; A61K47/26; A61K47/46; A61P1/00; A61P1/04; A61P25/00; A61P43/00; A61K38/08
Domestic Patent References:
JP2015503913A
JP2013507394A
JP2013537531A
Foreign References:
WO2014197562A1
WO2014036182A1
US20120252775
WO2014078911A1
WO2013176774A1
US20130266539
Other References:
Journal of Digestive Diseases (2014) vol.15, Suppl.1, p.118-119(PO-288)
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mihiro
Tatsuhiko Abe