Title:
CX3CR1修飾物質を用いる糖尿病の治療および診断の方法
Document Type and Number:
Japanese Patent JP2005528921
Kind Code:
A
Abstract:
The present invention provides compositions and methods for diagnosing and treating diabetes and insulin resistance. In particular, the invention provides methods of identifying modulators of CX3CR1 and using those modulators to treat diabetes, as well as methods of diagnosing diabetes by measuring the levels of CX3CR1 or fractalkine in a patient.
Inventors:
Moody Shona
Gustavson Thomas A.
Gustavson Thomas A.
Application Number:
JP2004511543A
Publication Date:
September 29, 2005
Filing Date:
June 10, 2003
Export Citation:
Assignee:
Metabolex Incorporated
International Classes:
C07K14/52; C07K14/715; C12N15/09; C12Q1/02; C12Q1/48; C12Q1/68; G01N33/15; G01N33/50; G01N33/53; G01N33/68; G01N33/74; (IPC1-7): C12N15/09; C12Q1/02; C12Q1/48; C12Q1/68; G01N33/15; G01N33/50; G01N33/53
Attorney, Agent or Firm:
Hatsushi Shimizu
Kazunori Hashimoto
Koichi Niimi
Kazunori Hashimoto
Koichi Niimi
Previous Patent: ＧＰＲ４５様／ＧＰＲ６３受容体のアゴニストまたはアンタゴニストを同...
Next Patent: 傷ついた組織または炎症組織と関係する疾患の診断および治療のための発...
Next Patent: 傷ついた組織または炎症組織と関係する疾患の診断および治療のための発...