Title:
メチル化CpGポリヌクレオチド
Document Type and Number:
Japanese Patent JP4673217
Kind Code:
B2
Abstract:
It is an object of the present invention to provide a polynucleotide, which can effectively suppress the immunoreactivity caused by DNA having a CpG motif and which can be used for preventing and/or treating immune-mediated diseases such as arthritis. The present invention provides a polynucleotide comprising a CpG motif wherein guanine is methylated, and a pharmaceutical composition comprising the above-mentioned polynucleotide.
Inventors:
Yukio Sato
Hiroko Kobayashi
Hiroko Kobayashi
Application Number:
JP2005505810A
Publication Date:
April 20, 2011
Filing Date:
April 23, 2004
Export Citation:
Assignee:
Yukio Sato
Taisho Pharmaceutical Co., Ltd.
Taisho Pharmaceutical Co., Ltd.
International Classes:
C12N15/09; A61K31/7088; A61P1/04; A61P3/10; A61P7/04; A61P7/06; A61P9/10; A61P11/02; A61P11/06; A61P17/00; A61P17/16; A61P19/02; A61P21/04; A61P25/00; A61P25/28; A61P29/00; A61P31/00; A61P31/04; A61P37/02; A61P37/06; A61P37/08; A61P43/00; C07H21/02; C07H21/04; C12N15/117
Foreign References:
| WO2001075092A2 | 2001-10-11 | |||
| WO2002074318A1 | 2002-09-26 | |||
| WO2000038693A1 | 2000-07-06 |
Attorney, Agent or Firm:
Patent Service Corporation Patent Office Sykes