Title:
ポリマー界面活性剤でカプセル封入された微小気泡および超音波画像形成でのその使用
Document Type and Number:
Japanese Patent JP3552721
Kind Code:
B2
Abstract:
PCT No. PCT/GB94/01923 Sec. 371 Date Mar. 14, 1997 Sec. 102(e) Date Mar. 14, 1997 PCT Filed Sep. 5, 1994 PCT Pub. No. WO95/06518 PCT Pub. Date Mar. 9, 1995The present invention relates to polymer-based gas-containing contrast agents in which microbubbles of gas are encapsulated by non-polymerizable wall-forming block or graft copolymer surfactants. The polymer surfactants are preferably biodegradable and include block and graft copolymers containing linkages of formula (I):-(O)m-CO-O-C(R1R2)-O-CO-(O)n-(I)where R1 and R2 each represent a hydrogen atom or a carbon-attached monovalent organic group, or R1 and R2 together form a carbon-attached divalent organic group and m and n are each zero or 1.
Inventors:
De Yugster, Haral
Huos, Per Antonius
Clave Enes, Yo
Let's Aether, Keith
Longway, Paul
Skultwairite, Lohr
Huos, Per Antonius
Clave Enes, Yo
Let's Aether, Keith
Longway, Paul
Skultwairite, Lohr
Application Number:
JP50801995A
Publication Date:
August 11, 2004
Filing Date:
September 05, 1994
Export Citation:
Assignee:
Amersham Health Aksuye Sersukapu
International Classes:
A61K49/00; A61K49/04; A61K49/22; B01J13/04; C08G63/08; C09K23/00; (IPC1-7): A61K49/00; A61K49/04; B01J13/04; C08G63/08
Foreign References:
| WO1992017212A1 | ||||
| WO1992017213A1 |
Attorney, Agent or Firm:
Chika Takagi
Tatsuo Sato
Kosuke Nishimura
Tatsuo Sato
Kosuke Nishimura