Title:
MICROCHEMICAL LUMINOUS ASSAY SYSTEM
Document Type and Number:
Japanese Patent JPS61159164
Kind Code:
A
Abstract:
A composition for use in a thermochemiluminescent assay. The composition includes a heme protein, a luminescer such as luminol, and serum albumin, the luminescer being noncovalently bonded to serum albumin. The composition may be used in a thermochemiluminescent for the ligant of a specific binding pair in which the composition is contacted with a fluid sample suspected of containing the antiligand of the specific binding pair and the subsequent light-emitting reaction is quantified. The specific binding light-emitting reaction is quantified. The specific binding pair can be, for instance, an enzyme and the substrate for which it is specific. The composition and the assay can be modified to detect ionizing radiation, peroxidative injury to cells, heat or a particular cell type.
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Inventors:
JIYONASAN ERU KIIRU
Application Number:
JP20989385A
Publication Date:
July 18, 1986
Filing Date:
September 21, 1985
Export Citation:
Assignee:
JIYONASAN ERU KIIRU
International Classes:
A61K35/12; C07K14/415; C07K14/76; C07K16/00; C07K17/06; C07K19/00; C12M1/34; C12M1/40; G01N33/52; C12Q1/28; C12Q1/32; G01N33/533; G01N33/543; G01N33/58; G01N33/76; (IPC1-7): A61K35/12; C07K17/06; C12M1/34; C12M1/40; C12Q1/28; G01N33/52; G01N33/543; G01N33/76
Attorney, Agent or Firm:
Kyozo Yuasa