Title:
マイクロカプセル化された物質及びそれらを作成する方法
Document Type and Number:
Japanese Patent JP4621022
Kind Code:
B2
Abstract:
A method of forming microspheres of a bioactive material, such as a protein polymer or drug by nebulizing a solubilized form of a material to be encapsulated and an encapsulating material, such as albumin, in a stirred chilled solvent system comprising a vegetable oil, mineral oil and/or a lower alcohol such that the formed microspheres demonstrate intracellular bioactivity when taken up by macrophages.
Inventors:
Martin J. Diesosa
Application Number:
JP2004531606A
Publication Date:
January 26, 2011
Filing Date:
August 27, 2003
Export Citation:
Assignee:
The Corporation of Macer University
International Classes:
A61K31/7088; A61K9/16; A61K9/50; A61K47/02; A61K47/08; A61K47/34; A61K47/42; A61K47/44; A61K48/00; B01J13/04; B01J13/14
Domestic Patent References:
| JP11514367A | ||||
| JP1115449A | ||||
| JP8505366A | ||||
| JP9508067A | ||||
| JP4500527A | ||||
| JP5507881A |
Foreign References:
| WO2002047659A1 | ||||
| US6402997 | ||||
| US5069936 | ||||
| US20020006912 | ||||
| WO1998044908A1 |
Attorney, Agent or Firm:
Masanori Nakamura