Title:
微粒子化ワルトン膠質
Document Type and Number:
Japanese Patent JP6640826
Kind Code:
B2
Abstract:
The present invention provides compositions and formulations of micronized Wharton's jelly having a controlled viscosity such that when delivered to the injured region of a subject, it remains substantially localized with little or no migration out of the injured region for the repair and/or regeneration thereof. Micronized Wharton's Jelly can be suspended in a pharmaceutically acceptable aqueous carrier, such as saline, sterile water, or any suitable buffer, to form a suspension or a gelatinous gel composition, or it can be in the form of a paste, suitable for delivery into the space adjacent the articular surface cartilage injured region of a subject. The micronized Wharton's jelly when employed at sufficient concentrations can be hydrated into a gel or paste and administered topically, or it can be injected into the body through the use of a needle and syringe. Accordingly, micronized Wharton's Jelly, compositions, or formulations thereof, can be delivered in a manner that is more convenient than Wharton's jelly that has not been micronized in accordance with the present invention.
Inventors:
Spencer, Randall
Sith, Somerly
Coob, thomas
Sith, Somerly
Coob, thomas
Application Number:
JP2017500060A
Publication Date:
February 05, 2020
Filing Date:
July 07, 2015
Export Citation:
Assignee:
Mimedix Group, Inc.
International Classes:
A61K35/51; A61K9/06; A61K9/08; A61P9/14; A61P29/00
Domestic Patent References:
| JP2014504944A | ||||
| JP2012505188A | ||||
| JP2005506121A |
Foreign References:
| WO2014058804A1 | ||||
| US20140050788 |
Attorney, Agent or Firm:
Ryoichi Takaoka
Nao Oda
Akiyo Iwahori
Kaoru Takahashi
Nao Oda
Akiyo Iwahori
Kaoru Takahashi