Title:
MICROREACTOR FOR BIOCHEMICAL REACTION
Document Type and Number:
Japanese Patent JP3654481
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide a microreactor for biochemical reaction capable of simultaneously carrying out a great number of biochemical reactions, for example, ≥1,000 reactions in parallel and performing not only a simple analysis but also a synthetic reaction of a substance such as protein on a cell.
SOLUTION: This microreactor comprises plural independent chambers formed by anisotropic etching on the surface of a single silicon base 12 and a flat plate 17 (heat-resistant glass) which is subjected to anode bonding on the surface of the silicon base 12 to seal up the reaction chambers. The reaction chambers have injection boats 14, an exhaust boat 15 and a channel 13 communicating with these boats. The injection boats 14 and the exhaust boat 15 are provided with through holes 16 communicating with the back of the silicone base, a reagent is injected through the through holes 16 to the injection boats 14 and discharged from the exhaust boat 15. Further, at least a part of the flat plate 17 is a transparent part and a reaction in the interior is optically observed through the transparent part.
Inventors:
Teruo Fujii
Hosokawa Kazuo
Takahiko Nojima
Isao Endo
Shoko Shuichi
Hosokawa Kazuo
Takahiko Nojima
Isao Endo
Shoko Shuichi
Application Number:
JP14796497A
Publication Date:
June 02, 2005
Filing Date:
June 05, 1997
Export Citation:
Assignee:
RIKEN
International Classes:
C12N15/09; B01F13/00; B01J19/00; B81B1/00; B81C1/00; C12M1/00; C12Q1/68; G01N37/00; (IPC1-7): C12M1/00
Domestic Patent References:
| JP7203998A | ||||
| JP8094472A |
Foreign References:
| WO1997000726A1 |
Attorney, Agent or Firm:
Minoru Hotta
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