Title:
脳疾患のミトコンドリア増強療法
Document Type and Number:
Japanese Patent JP2021532093
Kind Code:
A
Abstract:
本発明は、健康な機能的ミトコンドリアで富化された幹細胞、これらの細胞を含む医薬組成物、および疾患が後天性ミトコンドリア機能障害に関連する場合もしない場合もある脳疾患、障害、およびそれらの症状を治療するためにそれらを使用する方法を提供する。
Inventors:
Eve Guiohana, Natalie
Harvie, Uriel
Buxfan, Shmuel
Shah, Noah
Bramkin, Moriya
Harvie, Uriel
Buxfan, Shmuel
Shah, Noah
Bramkin, Moriya
Application Number:
JP2021502783A
Publication Date:
November 25, 2021
Filing Date:
July 22, 2019
Export Citation:
Assignee:
Minovia Therapeutics Limited
International Classes:
A61K35/28; A61K35/17; A61K35/18; A61K35/19; A61K35/51; A61K35/545; A61K45/00; A61P25/00; A61P43/00
Domestic Patent References:
| JP2018507690A | 2018-03-22 | |||
| JP2014501764A | 2014-01-23 |
Foreign References:
| WO2018101708A1 | 2018-06-07 | |||
| US20110008310A1 | 2011-01-13 |
Other References:
BABENKO VA. ET AL.: "Miro1 Enhances Mitochondria Transfer from Multipotent Mesenchymal Stem Cells (MMSC) to Neural Cells", MOLECULES, vol. 23巻3号, JPN6023025713, 19 March 2018 (2018-03-19), pages 687 - 1, ISSN: 0005092415
GOLLIHUE JL. ET AL.: "Mitochondrial transplantation strategies as potential therapeutics for central nervous system trauma", NEURAL REGEN RES, vol. 13巻2号, JPN6023025714, February 2018 (2018-02-01), pages 194 - 197, ISSN: 0005092416
TORRALBA D. ET AL.: "Mitochondria Know No Boundaries: Mechanisms and Functions of Intercellular Mitochondrial Transfer", FRONT CELL DEV BIOL., vol. 4巻, JPN6023025712, 2016, pages 00107 - 1, ISSN: 0005092417
GOLLIHUE JL. ET AL.: "Mitochondrial transplantation strategies as potential therapeutics for central nervous system trauma", NEURAL REGEN RES, vol. 13巻2号, JPN6023025714, February 2018 (2018-02-01), pages 194 - 197, ISSN: 0005092416
TORRALBA D. ET AL.: "Mitochondria Know No Boundaries: Mechanisms and Functions of Intercellular Mitochondrial Transfer", FRONT CELL DEV BIOL., vol. 4巻, JPN6023025712, 2016, pages 00107 - 1, ISSN: 0005092417
Attorney, Agent or Firm:
Ryoichi Takaoka
Nao Oda
Akiyo Iwahori
Rena Miyoshi
Kaoru Takahashi
Nao Oda
Akiyo Iwahori
Rena Miyoshi
Kaoru Takahashi
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