Title:
修飾型Cpn10およびPRRシグナル伝達
Document Type and Number:
Japanese Patent JP2011519548
Kind Code:
A
Abstract:
The present invention relates to isolated Cpn10 polypeptides possessing an increased affinity for a PRR ligand compared to Ala Cpn10 polypeptide. In a further embodiment, the present invention also relates to modified chaperonin 10 polypeptides, and to nucleic acids encoding the same and to compositions comprising such polypeptides and uses thereof.
Inventors:
Naylor Dean Jason
Brown richard james
Howard Christopher Bulls
Devacker Christopher John
Ward Linda Allison
Stock Janet Elizabeth
James Andrew Ray
Lambert Daniel Scott
Ralston Kylie Jane
Van Human Walter Rene Antonius
Brown richard james
Howard Christopher Bulls
Devacker Christopher John
Ward Linda Allison
Stock Janet Elizabeth
James Andrew Ray
Lambert Daniel Scott
Ralston Kylie Jane
Van Human Walter Rene Antonius
Application Number:
JP2011503310A
Publication Date:
July 14, 2011
Filing Date:
April 09, 2009
Export Citation:
Assignee:
Sea Bio Limited
International Classes:
C12N15/09; A61K31/7088; A61K38/00; A61K39/395; A61P3/10; A61P9/10; A61P11/06; A61P17/06; A61P25/00; A61P25/28; A61P29/00; A61P31/04; A61P31/10; A61P31/12; A61P31/18; A61P35/00; A61P37/00; A61P37/08; C07K14/47; C07K16/18; C12N1/15; C12N1/19; C12N1/21; C12N5/10; G01N33/15; G01N33/50; G01N37/00
Domestic Patent References:
| JP2007517808A | 2007-07-05 |
Foreign References:
| WO2007025343A1 | 2007-03-08 | |||
| WO2007006095A2 | 2007-01-18 | |||
| WO2007045046A1 | 2007-04-26 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto