Title:
改変された第VII因子ポリペプチドおよびその使用
Document Type and Number:
Japanese Patent JP2011517942
Kind Code:
A
Abstract:
Modified factor VII polypeptides and uses thereof are provided. Such modified FVII polypeptides include Factor VIIa and other forms of Factor VII. Among modified FVII polypeptides provided are those that have altered 5 activities, typically altered procoagulant activity, including increased procoagulant activities. Hence, such modified polypeptides are therapeutics.
Inventors:
Edwin El Madison
Christopher Thanos
Christopher Thanos
Application Number:
JP2011504007A
Publication Date:
June 23, 2011
Filing Date:
April 10, 2009
Export Citation:
Assignee:
CATALYST BIOSCIENCES, INC.
International Classes:
C12N15/09; A61K31/122; A61K31/58; A61K35/12; A61K35/14; A61K35/18; A61K35/76; A61K38/43; A61K38/46; A61K38/48; A61K45/00; A61K48/00; A61P7/04; C07K14/745; C12N5/10
Foreign References:
| WO2007031559A2 | 2007-03-22 | |||
| WO2008090215A1 | 2008-07-31 |
Other References:
JPN6013033229; ＦＥＢＳ Ｌｅｔｔｅｒｓ Ｖｏｌ．５８１, 2007, ｐ．７１-７６
JPN6013033230; Ｐｒｏｃ． Ｎａｔｌ． Ａｃａｄ． Ｓｃｉ． Ｖｏｌ．９３, 1996, ｐ．１４３７９-１４３８４
JPN6013033230; Ｐｒｏｃ． Ｎａｔｌ． Ａｃａｄ． Ｓｃｉ． Ｖｏｌ．９３, 1996, ｐ．１４３７９-１４３８４
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Kenji Tomita
Mina Shiga
Masayuki Nakagawa
Fumio Inai
Manami Sawamoto
Hiroshi Yamazaki
Kenji Tomita
Mina Shiga
Masayuki Nakagawa
Fumio Inai
Manami Sawamoto