修飾ステロールアシルトランスフェラーゼ

Title:

修飾ステロールアシルトランスフェラーゼ

Document Type and Number:

Japanese Patent JP7460540

Kind Code:

B2

Abstract:

The present invention is related to modified sterol acyltransferase enzymes with improved activity and/or specificity towards acylation of the vitamin D3 precursor 7-dehydrocholesterol (7-DHC) to be used in biotechnological production of vitamin D3. The invention further relates to a yeast strain expressing said modified enzymes and their use in a process for production of vitamin D3 or derivatives and/or metabolites thereof.

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Inventors:

Farrell, Christopher, Mark
Laprade, Lisa, Ann
Lehmann, Otto, Martin
true heart, joshua

Application Number:

JP2020557258A

Publication Date:

April 02, 2024

Filing Date:

May 21, 2019

Export Citation:

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Assignee:

DSM IP ASSETS B.V.

International Classes:

C12N9/10; C12N1/19; C12P33/00

Domestic Patent References:

JP2012024084A
JP2010534479A
JP2007516717A
JP2003508052A
JP2013502903A

Foreign References:

WO2017108799A1

Attorney, Agent or Firm:

Ikeda Adult
Yoshinori Shimizu
Junichiro Sakamaki

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