Title:
糖質コルチコイド受容体のモジュレーター
Document Type and Number:
Japanese Patent JP4503436
Kind Code:
B2
Abstract:
The present invention provides compounds of the formula wherein A is of the formula and X, Y, n, R1-R25 are as described in the specification which are modulators of the glucocorticoid receptor and are thus useful for the treatment of animals requiring glucocorticoid receptor agonist therapy. Glucocorticoid receptor modulators are useful in the treatment of certain inflammatory conditions.
Inventors:
Eve Andre Santini
Edward Fox Kleinman
Ralph Pelton Robinson, Jr.
Edward Fox Kleinman
Ralph Pelton Robinson, Jr.
Application Number:
JP2004519100A
Publication Date:
July 14, 2010
Filing Date:
June 25, 2003
Export Citation:
Assignee:
Pfizer Products Inc.
International Classes:
C07C39/23; A61K31/047; A61K31/41; A61K31/4245; A61K31/427; A61K31/44; A61K31/4439; A61K31/4453; A61K31/454; A61K31/495; A61K31/5375; A61K31/5377; A61P1/00; A61P5/00; A61P5/46; A61P7/00; A61P11/02; A61P17/00; A61P27/02; A61P29/00; A61P35/00; A61P37/00; A61P43/00; C07C35/37; C07C35/42; C07C39/17; C07C39/42; C07C43/23; C07C49/747; C07C49/755; C07C49/83; C07C59/125; C07C59/72; C07C69/712; C07C205/57; C07C215/44; C07C215/64; C07C235/06; C07C235/20; C07C255/13; C07C255/24; C07C255/29; C07C255/53; C07C271/52; C07D213/30; C07D213/40; C07D257/04; C07D271/06; C07D277/24; C07D295/092; C07D295/185; C07D403/06; C07D413/06; C07D413/12; C07D413/14
Domestic Patent References:
| JP2002543169A | ||||
| JP2002193911A | ||||
| JP2002193937A |
Foreign References:
| EP1097709B1 |
Other References:
PEGEL,K.H. et al,Constitution of the aromatic diterpene cleistanthol,Journal of the Chemical Society [Section] C: Organic,1971年,No.5,p.904-9
GOVINDAN,S.V. et al,Regiospecific quassinoidal A-ring synthesis via an olefin oxidation strategy,Journal of Organic Chemistry,1988年,Vol.53, No.11,p.2593-7
GOVINDAN,S.V. et al,Regiospecific quassinoidal A-ring synthesis via an olefin oxidation strategy,Journal of Organic Chemistry,1988年,Vol.53, No.11,p.2593-7
Attorney, Agent or Firm:
Chika Takagi
Junji Yuda
Shoji Miwa
Junji Yuda
Shoji Miwa