Title:
MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS
Document Type and Number:
Japanese Patent JP2015120762
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide compounds useful as modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR").SOLUTION: A compound represented by the general formula I or a pharmaceutically acceptable salt thereof is provided, where R, R, ring A, ring B, and n in the formula are defined in the specifications.
Inventors:
RUAH SARA S HADIDA
GROOTENHUIS PETER D J
VAN GOOR FREDERICK
ZHOU JINGLAN
BEAR BRIAN
MILLER MARK T
MCCARTNEY JASON
NUMA MEHDI MICHEL JAMEL
GROOTENHUIS PETER D J
VAN GOOR FREDERICK
ZHOU JINGLAN
BEAR BRIAN
MILLER MARK T
MCCARTNEY JASON
NUMA MEHDI MICHEL JAMEL
Application Number:
JP2015073706A
Publication Date:
July 02, 2015
Filing Date:
March 31, 2015
Export Citation:
Assignee:
VERTEX PHARMA
International Classes:
C07D209/08; A61K31/404; A61K31/405; A61K31/407; A61K31/41; A61K31/4184; A61K31/4192; A61K31/4439; A61K31/454; A61P11/00; A61P43/00; C07D403/12; C07D405/12; C07D405/14; C07D413/12; C07D487/04
Domestic Patent References:
| JP5420395B2 | 2014-02-19 | |||
| JP2007502253A | 2007-02-08 | |||
| JP2006513159A | 2006-04-20 | |||
| JP2006505571A | 2006-02-16 | |||
| JPS61178963A | 1986-08-11 | |||
| JP2004537541A | 2004-12-16 | |||
| JP5827297B2 | 2015-12-02 |
Foreign References:
| WO2005075435A1 | 2005-08-18 | |||
| WO2006002421A2 | 2006-01-05 | |||
| WO2007056341A1 | 2007-05-18 |
Attorney, Agent or Firm:
Takuji Yamada
Aoyama Aoi
Michiko Matsutani
Yasushi Ochiai
Aoyama Aoi
Michiko Matsutani
Yasushi Ochiai