Title:
真皮繊維芽細胞の３種の亜集団の分子シグネチャー及びこれらの亜集団のうちの１種を含む真皮等価物
Document Type and Number:
Japanese Patent JP7399083
Kind Code:
B2
Abstract:
The object of this invention is a method of in vitro identification of a dermal fibroblast as being a papillary fibroblast, a reticular fibroblast or a dermal-hypodermal junction fibroblast (FJDH), comprising a step of measuring the level of an expression product of at least one gene selected from the group consisting in the UCP2 and FGF9, and optionally the COL11 A1 and ACAN genes, and the level of an expression product of the KLF9 gene.
Inventors:
Valerie Adon
Daniel Aselinaud
Daniel Aselinaud
Application Number:
JP2020518055A
Publication Date:
December 15, 2023
Filing Date:
September 27, 2018
Export Citation:
Assignee:
LOREAL
L'OREAL
L'OREAL
International Classes:
C12Q1/04; C12M1/34; C12N5/071; C12N15/09; C12N15/12; C12Q1/6806; C12Q1/6813; C12Q1/6851; C12Q1/6869; C12Q1/6874; G01N33/53; G01N37/00
Domestic Patent References:
| JP2010155834A | ||||
| JP2014533959A |
Other References:
Journal of Investigative Dermatology,2017年,137,pp.1787-1789 ,& SUPPLEMENTARY MATERIALS AND METHODS
Technical Note : Design and Performance of the GeneChipHuman Genome U133 Plus 2.0 and Human Genome U133A 2.0 Arrays,2017年 5月17日,[2021年12月23日検索],インターネット
Technical Note : Design and Performance of the GeneChipHuman Genome U133 Plus 2.0 and Human Genome U133A 2.0 Arrays,2017年 5月17日,[2021年12月23日検索],インターネット
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mihiro
Kentaro Horie
Shinya Mihiro
Kentaro Horie