Title:
創傷、特に慢性創傷の処置のための分子標的
Document Type and Number:
Japanese Patent JP6473155
Kind Code:
B2
Abstract:
The present invention relates to a therapeutic compound comprising:
- an agent that inhibits the activity of at least one gene selected from the group consisting of MEOX2, SIX2 and homologues thereof having at least 50% identity with said genes
and/or
- an agent that enhances the activity of at least one gene selected from the group consisting of CREB5, E2F1, EGR2, HIC1, IRF7, JUN, MYC, SRF, STAT4, TCF4, FOXS1, GLI1, SOX9 and homologues thereof having at least 50% identity with said gene
for use in the treatment of wounds, preferably chronic wounds.
Inventors:
Dugast-Darzac Clair
Noize Mete
Dalzac Xavier
Spirutini Ebert Beatrice
Noize Mete
Dalzac Xavier
Spirutini Ebert Beatrice
Application Number:
JP2016532316A
Publication Date:
February 20, 2019
Filing Date:
July 30, 2014
Export Citation:
Assignee:
Yurgo Lecherche Innovasion Edevropmann
Center Nacional de la Shellche Scientific
Universites Paris Didelo-Paris 7
Insam (Institut National de la Sante d'Erchelche Medical)
Ecole Normal Sperule
Center Nacional de la Shellche Scientific
Universites Paris Didelo-Paris 7
Insam (Institut National de la Sante d'Erchelche Medical)
Ecole Normal Sperule
International Classes:
A61K48/00; A61K31/7105; A61K31/711; A61K31/713; A61K35/76; A61K45/00; A61P17/02
Domestic Patent References:
| JP2000510333A | ||||
| JP2006503006A | ||||
| JP2010280651A |
Foreign References:
| WO2012120269A1 |
Other References:
J. Clin. Oncol,2013年 2月 1日,Vol. 31, No. 4,pp. 482-489
Biochem. Biophys. Res. Commun.,2003年,Vol. 310,pp. 318-326
Biochem. Biophys. Res. Commun.,2006年,Vol. 339,pp. 1089-1097
Biochem. Biophys. Res. Commun.,2003年,Vol. 310,pp. 318-326
Biochem. Biophys. Res. Commun.,2006年,Vol. 339,pp. 1089-1097
Attorney, Agent or Firm:
Masayuki Masabayashi
Hayashi Ichiyoshi
Hayashi Ichiyoshi