Title:
MONOCLONAL ANTIBODY
Document Type and Number:
Japanese Patent JP3522735
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide a monoclonal antibody which is specific to a protein inducing production of IFN-γ in an immunocompetent cell and a hybridoma capable of producing the monoclonal antibody and use thereof.
SOLUTION: The monoclonal antibody which is specific to the protein having specific physicochemical properties, the hybridoma capable of producing the monoclonal antibody, a method for producing the monoclonal antibody comprising a step for culturing the monoclonal antibody in vivo or in vitro and a step for collecting the monoclonal antibody from the cultured product or the body fluid thereof, a method for purifying the protein comprising a step for absorbing the protein into the monoclonal antibody by bringing the monoclonal antibody into contact with a mixture containing the protein and foreign materials and a step for desorbing the absorbed protein from the monoclonal antibody and a method for detecting the protein comprising bringing the monoclonal antibody into contact with a sample to be examined and detecting the protein by immune reaction are provided.
Inventors:
Kunikata, Toshio
Taniguchi, Mutsuko
Kono, Keizo
Kurimoto, Masashi
Taniguchi, Mutsuko
Kono, Keizo
Kurimoto, Masashi
Application Number:
JP2002226077A
Publication Date:
April 26, 2004
Filing Date:
February 10, 1995
Export Citation:
Assignee:
HAYASHIBARA BIOCHEM LAB INC
International Classes:
C12N15/09; C07K16/24; (IPC1-7): C07K16/24
Other References:
Ｉｎｆｅｃｔ．Ｉｍｍｕｎ．，Ｖｏｌ．６１，Ｎｏ．１（１９９３）ｐ．６４−７０