Title:
多孔質層上に試薬を含む複層化された電気化学系微小流体センサー
Document Type and Number:
Japanese Patent JP2006516721
Kind Code:
A
Abstract:
The present invention relates to a microfluidic electrochemical sensor apparatus and a method for conducting analytical tests with said apparatus for multi-reactant assays. The apparatus of this invention is a multi-layer body made of at least three layers, the first one being a polymer layer ( 1 ) comprising a microstructure ( 5 ) with at least one integrated microelectrode ( 4 ) and conductive tracks ( 13 ) for connection to an external electrochemical unit, the second one being a non-porous material serving to cover said microstructure so as to enable microfluidic manipulations and the third one being a porous layer ( 2 ) such as a membrane or a glass frit, said porous layer comprising at least one reagent ( 3 ) to be solubilized upon contact with a test solution ( 7 ) and reacting with an analyte ( 6 ) present in said solution to form a product that is transported along said microstructure so as to enable electrochemical detection of said analyte. The invention notably enables the performance of multi-reactant assays in a reduced number of steps.
Inventors:
Rossiere, Joel Stefan
Raymond, Fredrick
Moliere, Patrick
Raymond, Fredrick
Moliere, Patrick
Application Number:
JP2006500022A
Publication Date:
July 06, 2006
Filing Date:
January 14, 2004
Export Citation:
Assignee:
Diagno Swiss Society Anonymous
International Classes:
G01N27/327; B01L3/00; G01N27/02; G01N27/30; G01N27/403; G01N27/416; G01N27/48; G01N27/62; G01N33/487; G01N33/543; G01N37/00
Domestic Patent References:
| JP2002195972A | 2002-07-10 | |||
| JP2001201479A | 2001-07-27 | |||
| JP2001061497A | 2001-03-13 | |||
| JPH1090214A | 1998-04-10 | |||
| JPH09196920A | 1997-07-31 | |||
| JP2000230916A | 2000-08-22 | |||
| JP2001201480A | 2001-07-27 |
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Tetsuji Koga
Hiroyuki Onoda
Masaya Nishiyama
Takashi Ishida
Tetsuji Koga
Hiroyuki Onoda
Masaya Nishiyama