Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
メチル化ＤＮＡの多重検出方法
Document Type and Number:
Japanese Patent JP6968894
Kind Code:
B2
Abstract:
The present disclosure relates to a method of detecting methylation of target DNA in a multiplex manner and a composition for detecting methylation of target DNA, and more particularly to a method for detecting methylation of target DNA, comprising: constructing an oligonucleotide, which comprises a target-specific sequence capable of binding complementarily to the target DNA and a universal primer that does not bind complementarily to the target DNA; linearly amplifying the target DNA for linear target enrichment by using the oligonucleotide as a primer; and amplifying the linearly amplified target DNA using an oligonucleotide, which is capable of binding complementarily to the linearly amplified target DNA, a universal primer, and a probe.

More Like This:
JP6658796Nucleic acid amplification method
JP3801865Method of removing nucleic acid contamination in amplification reaction
Inventors:
Anson fan
Otejon
Application Number:
JP2019540498A
Publication Date:
November 24, 2021
Filing Date:
September 29, 2017
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
GENOMICTREE,INC.
International Classes:
C12Q1/6848; C12Q1/6816; C12Q1/6837; C12Q1/6851; C12Q1/6853; C12Q1/686; C12Q1/6869; C12Q1/6876; C12Q1/6886; G01N33/53
Foreign References:
US20100028890
US20120252013
US20100144867
Other References:
Methods in enzymology,1993年,Vol.225,p.567-583
the journal of molecular diagnostics,2013年,Vol.15,p.498-507
Clinical epigenetics,2017年,Vol.9:126,DOI 10.1186/s13148-017-0426-3
The journal of molecular diagnostics,2013年,Vol.15,p.498-507
BMC Genomics,2015年,Vol.16:350,DOI 10.1186/s12864-015-1572-7
Attorney, Agent or Firm:
Kenjiro Yamaguchi
Hironori Nagayama
Kenichi Morita



 
Previous Patent: Light emitting device

Next Patent: Method and optical system to acquire tomographic distribution of electromagnetic field crest