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Title:
複数トランスジーン組み換えアデノウイルス
Document Type and Number:
Japanese Patent JP7301748
Kind Code:
B2
Abstract:
The invention relates to a recombinant adenovirus comprising two or more therapeutic transgenes, e.g., two components of a heterodimeric cytokine, separated by a cleavable linker.

Inventors:
Reed, Tony, Earl.
Larson, Christopher
Olonski, Bryan, Tee.
Application Number:
JP2019555915A
Publication Date:
July 03, 2023
Filing Date:
April 12, 2018
Export Citation:
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Assignee:
Epicentre X, Inc.
International Classes:
C12N7/01; A61K35/761; A61K48/00; A61P35/00; A61P43/00; C12N15/861
Domestic Patent References:
JP2006526409A
Foreign References:
WO2014170389A1
WO2004108893A2
WO2010101921A2
Other References:
YUAN S. et al.,Oncotarget,2016年,Vol.7 No.37,p.60491-60502
RODRIGUEZ-GARCIA A. et al,Gene Therapy,2015年,22,p.596-601
GAKEN J. et al.,Gene Therapy,2000年,7,p.1979-1985
Attorney, Agent or Firm:
Yoshinori Hosoda