Title:
多重特異性抗原結合タンパク質及びその使用方法
Document Type and Number:
Japanese Patent JP7115991
Kind Code:
B2
Abstract:
Disclosed herein are multispecific, such as bispecific, antigen binding proteins comprising a first antigen binding domain comprising a heavy chain variable domain and a light chain variable domain, and a second antigen binding domain comprising a single-domain antibody. Pharmaceutical compositions comprising the multispecific antigen binding proteins, kits and methods of use thereof are further provided.
Inventors:
Chow, Chuan-chu
Jean, Yaphen
Woo Shu
Liu, Zhenyu
Li, Zhongdao
Jiang, Fanlian
Jean, Yaphen
Woo Shu
Liu, Zhenyu
Li, Zhongdao
Jiang, Fanlian
Application Number:
JP2018569033A
Publication Date:
August 09, 2022
Filing Date:
July 20, 2017
Export Citation:
Assignee:
NANJING LEGEND BIOTECH CO.,LTD.
International Classes:
C07K16/46; A61K39/395; A61P1/04; A61P11/06; A61P17/06; A61P19/02; A61P29/00; A61P35/00; A61P37/06; C07K16/28
Domestic Patent References:
| JP2013505923A | ||||
| JP2014090721A | ||||
| JP2011504742A | ||||
| JP2008523795A | ||||
| JP2015504306A | ||||
| JP2009504191A |
Foreign References:
| WO2006138670A2 |
Other References:
監修 植田 充美,抗体医薬の最前線,2007年07月20日,p. 4-5
Robert Mabry et al.,Protein Engineering, Design & Selection,2009年12月18日,vol. 23, no. 3,p. 115-127
Aifen Li et al.,AMB Expr.,2016年,Vol. 6, no. 32,全8頁
Li Li et al.,J Immunother.,2015年12月,Vol. 38, no. 9,p. 350-356
Robert Mabry et al.,Protein Engineering, Design & Selection,2009年12月18日,vol. 23, no. 3,p. 115-127
Aifen Li et al.,AMB Expr.,2016年,Vol. 6, no. 32,全8頁
Li Li et al.,J Immunother.,2015年12月,Vol. 38, no. 9,p. 350-356
Attorney, Agent or Firm:
Shusaku Yamamoto
Morishita Natsuki
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Morishita Natsuki
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
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