Title:
癌を治療するための多価ＰＤ－Ｌ１結合化合物
Document Type and Number:
Japanese Patent JP7381604
Kind Code:
B2
Abstract:
This invention provides methods and materials for treating cancer. The invention encompasses methods and materials for delivering programmed death-ligand 1 (PD-L1) binding compounds and/or compositions containing one or more monovalent or multivalent programmed death-ligand 1 (PD-L1) binding compounds which are administered to a mammal having cancer to treat the mammal. In some cases, a multivalent PD-L1 binding compound can include two or more programmed cell death protein 1 (PD-1) polypeptides (and/or fragments thereof having the ability to bind PD-L1). This invention also provides methods and materials for making multivalent PD-L1 binding compounds and methods and materials for making nucleic acid molecules that encode PD-L1 binding compounds.
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Inventors:
Barry Michael Ay
Application Number:
JP2021564249A
Publication Date:
November 15, 2023
Filing Date:
April 28, 2020
Export Citation:
Assignee:
Mayo Foundation for Medical Education and Research
International Classes:
C12N7/01; A61K38/17; A61K47/00; A61K47/62; A61K48/00; A61P35/00; C07K14/075; C07K19/00; C12N15/62; C12N15/861
Domestic Patent References:
| JP2015506372A |
Foreign References:
| WO2018157165A1 | ||||
| WO2018006005A1 |
Attorney, Agent or Firm:
Mitsufumi Ezaki
Blacksmith Minoru Sawa
Katsuri Uenishi
Ichiro Torayama
Taisei Ishida
Blacksmith Minoru Sawa
Katsuri Uenishi
Ichiro Torayama
Taisei Ishida