Title:
多価キメラOSPCワクシノーゲンおよび診断用抗原
Document Type and Number:
Japanese Patent JP2013542942
Kind Code:
A
Abstract:
A chimeric polyvalent recombinant protein for use as a vaccine and diagnostic for Lyme disease is provided. The chimeric protein comprises epitopes of the loop 5 region and/or the alpha helix 5 region of outer surface protein C (OspC) types. The OspC types may be associated with mammalian Borrelia infections.
Inventors:
Markoni, Richard Tea.
Earn heart, christopher
Earn heart, christopher
Application Number:
JP2013535034A
Publication Date:
November 28, 2013
Filing Date:
October 19, 2011
Export Citation:
Assignee:
Virginia Commonwealth University
International Classes:
C07K14/20; A61K39/00; A61K39/395; A61P31/04; C07K14/195; C07K16/12; C07K19/00; G01N33/53; C12N15/09
Domestic Patent References:
| JP2002523019A | 2002-07-30 | |||
| JP2009519244A | 2009-05-14 | |||
| JP2010509217A | 2010-03-25 |
Foreign References:
| WO2000078966A1 | 2000-12-28 |
Other References:
JPN6015037107; Ｈｕｍ． Ｖａｃｃｉｎ． Ｖｏｌ．３， Ｎｏ．６, 200712, ｐ．２８１-２８９
JPN6015037111; Ｖａｃｃｉｎｅ Ｖｏｌ．２５， Ｎｏ．１７, 20070430, ｐ．３４１９-３４２７
JPN6015037111; Ｖａｃｃｉｎｅ Ｖｏｌ．２５， Ｎｏ．１７, 20070430, ｐ．３４１９-３４２７
Attorney, Agent or Firm:
Shin Uchihara