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Title:
MULTIVALENT PNEUMOCOCCAL POLYSACCHARIDE-PROTEIN CONJUGATE COMPOSITION
Document Type and Number:
Japanese Patent JP2013006881
Kind Code:
A
Abstract:

To encourage use of 6A and 19A capable of wider application than Prevnar, which are independent of the limitation of serogroup cross protection.

Provided is a multivalent immunogenic composition containing 13 different kinds of polysaccharide-protein conjugates together with a physiologically acceptable vehicle. Each of the conjugates contains a capsular polysaccharide from a different serotype of Streptococcus pneumoniae conjugated with a carrier protein. The formulation, if desired, includes an aluminum-based adjuvant etc. More specifically, provided is a Pneumococcal conjugate (13vPnC) composition that contains six kinds of serotypes (1, 3, 5, 6A, and 7F and 19A) in addition to seven kinds of serotypes (4, 6B, 9V, 14, 18C, and 19F and 23F) of 7vPnC vaccine.


Inventors:
HAUSDORFF WILLIAM P
SIBER GEORGE RAINER
PARADISO PETER R
Application Number:
JP2012000225307
Publication Date:
January 10, 2013
Filing Date:
October 10, 2012
Export Citation:
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Assignee:
WYETH LLC
International Classes:
A61K39/09; A61K39/116; A61K39/385; A61K39/39; A61P31/04
Domestic Patent References:
JP2002539273A2002-11-19
JP2004508416A2004-03-18
JP2002540074A2002-11-26
JP2002542204A2002-12-10
JP2004501873A2004-01-22
JP2002540075A2002-11-26
Foreign References:
Other References:
JPN7015000525; American Journal of Epidemiology 2004、159(7):634-6
JPN7015000526; Seminars in Pediatric Infectious Diseases 2002、13(
JPN7015000527; Clinical Infectious Diseases 2000、30:100-121
JPN7015000528; The Pediatric Infectious Disease Journal 2002、21(1
JPN7015000529; International Journal of Medical Microbiology 2004
Attorney, Agent or Firm:
室伏 良信
▲高▼橋 宏次
宮澤 純子
四本 能尚
佐藤 眞紀
龍田 美幸